Rbm38 hif1
WebDownload scientific diagram RBM38 directly binds to HIF1α 5′ and 3′ UTRs. (A) Whole cell lysates from H1299 cells were collected and immunoprecipitated with anti-RBM38 … WebMar 9, 2024 · RNA binding Motif protein-38 regulates myocardial hypertrophy in LXR-alpha-dependent lipogenesis pathway. [RBM38 Mediates the Proliferation of Acute Myeloid …
Rbm38 hif1
Did you know?
WebFeb 15, 2024 · The p63 transcription factor, a p53 family protein, regulates genes involved in various cellular processes, including cell growth and differentiation. We previously showed that RNA-binding motif protein (Rbm38) is a p63 target and, in turn, regulates p63α mRNA stability by binding to the AU/U-rich e … WebHere, we review the evidence that RBM38, an intensively studied RBP, frequently plays a tumor-suppressive role in multiple human cancer types. Genetic studies in mice deficient …
WebThe RNA Binding Protein RBM38 (RNPC1) Regulates Splicing during Late Erythroid Differentiation Laurie A. Heinicke1¤a, Behnam Nabet2¤b, Shihao Shen3,4, Peng Jiang3¤c, Sebastiaan van Zalen1, Benjamin Cieply1, J. Eric Russell1,5, Yi Xing3,4, Russ P. Carstens2,6* 1 Department of Medicine (Hematology-Oncology Division), Perelman School of Medicine, … WebMar 9, 2024 · RNA binding Motif protein-38 regulates myocardial hypertrophy in LXR-alpha-dependent lipogenesis pathway. [RBM38 Mediates the Proliferation of Acute Myeloid Leukemia Cells HL-60 by Regulating FZD1 mRNA Stability]. RNA-binding protein RBM38 inhibits colorectal cancer progression by partly and competitively binding to PTEN 3'UTR …
Webfrom publication: Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNAbinding protein and a p53 family target, ... (HIF1), a heterodimeric transcription factor, ... WebJul 8, 2024 · RBM38 is located on chromosome 20q13.31 and is highly expressed in a variety of human tissues (RPKM > 4 in 19 of 27 tissues; Fig. 1).Comparative phylogenic …
WebHypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation Seong-Jun Cho 1 ... HIF1 alpha (HIF1α) and HIF1β …
Webfactor family are targeted by Rbm38, either through RNA stability or RNA translation. Among these family members, Rbm38 stabilizes mRNAs of p21 and p73, while it destabilizes p63 mRNA [9, 11, 22]. Interestingly, phosphorylation of Rbm38 by glycogen synthase kinase 3 (GSK3) converts Rbm38 from a translational repressor to an activator [24 ... chip\u0027s i5WebMar 21, 2024 · RBM38 (RNA Binding Motif Protein 38) is a Protein Coding gene. Diseases associated with RBM38 include Lung Cancer and Erythema Infectiosum . Gene Ontology … graphic card for dell optiplex 9020WebNov 16, 2014 · HIF1 belongs to a subfamily of the basic-helix-loop-helix-PAS transcription factors . In response to high levels of oxygen, HIF1α protein is modified by prolyl hydroxylase and rapidly degraded through the VHL-mediated proteasomal pathway . Once ... RBM38 prevents eIF4E from binding HIF1α transcript (A) ... chip\u0027s itchip\u0027s isWebNov 23, 2024 · Objective The study is to research how miR-34-SIRT1 is regulated during hypoxia in lung cancer cells. Results Analysis of publicly available datasets from patients … graphic card for h61 motherboardWebThe possibility of targeting and integrating RBM38 and LXR-α as a therapeutic approach against car-diac remodeling has never been investigated. Herein, we provide evidence to support that RBM38 is a potential modulator of myocardial hypertrophy via the LXR-α-Dependent lipogenesis pathway. graphic card for gaming pcWebAug 17, 2012 · RBM38 was shown to be necessary for proper p53 function, ... may be resistant to hypoxia not only because of decreased apoptosis and senescence but also because of increased HIF1 signalling, ... chip\u0027s iv